Description

1-(4-Fluorophenyl)-6-Oxo-4-(Propylsulfanyl)-1,6-Dihydro-3-Pyridazinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct pyridazinecarboxylic acid core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in early-stage drug discovery programs.
• Process Development & Scale-up: Employed in the development and optimization of robust, scalable synthetic routes for API manufacturing under cGMP conditions.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects requiring high-fidelity, fluorinated heterocyclic compounds.
• Academic Research: Utilized in university and institutional labs for studying novel organic reactions and the properties of fluorinated pyridazine derivatives.

Basic Information

Product Name	1-(4-Fluorophenyl)-6-Oxo-4-(Propylsulfanyl)-1,6-Dihydro-3-Pyridazinecarboxylic Acid
CAS No.	339096-33-2
Molecular Formula	C14H13FN2O3S
Molecular Weight	308.33 g/mol
Synonyms	4-(Propylthio)-1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylic acid; 1-(4-Fluorophenyl)-4-(propylsulfanyl)-6-oxo-1,6-dihydro-3-pyridazinecarboxylic acid; 1-(p-Fluorophenyl)-6-oxo-4-(propylthio)-1,6-dihydro-3-pyridazinecarboxylic acid; 4-(Propylsulfanyl)-1-(4-fluorophenyl)-6-oxo-1,6-dihydro-3-pyridazinecarboxylic acid; CAS 339096-33-2
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-6-Oxo-4-(Propylsulfanyl)-1,6-Dihydro-3-Pyridazinecarboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with research and development grade specifications. Our quality system is designed to support regulatory filings and ensure batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is stable under these conditions but should be kept away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.