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Ethyl 5-Chloro-2,3-Dihydro-2-(4-Fluorophenyl)Pyridazin-3-One-6-Carboxylat CAS NO 339031-90-2


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CAS No.:339031-90-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl 5-Chloro-2,3-Dihydro-2-(4-Fluorophenyl)Pyridazin-3-One-6-Carboxylat is a high-purity, advanced pharmaceutical intermediate belonging to the pyridazinone class of heterocyclic compounds. Its core value lies in its role as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular scaffolds. This compound is essential for research and development chemists and manufacturers in the global pharmaceutical and agrochemical industries seeking to develop new drug candidates or crop protection agents.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
  • Agrochemical Research: Serves as a foundational structure for developing new herbicides and fungicides with specific modes of action.
  • Chemical Synthesis Building Block: Used in organic synthesis for constructing complex heterocyclic molecules in medicinal chemistry programs.
  • Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for pharmacological and structure-activity relationship (SAR) studies.
  • Process Development & Scale-Up: Utilized by process chemists to develop and optimize scalable, cost-effective synthetic routes for target molecules.

Basic Information

Product Name Ethyl 5-Chloro-2,3-Dihydro-2-(4-Fluorophenyl)Pyridazin-3-One-6-Carboxylat
CAS No. 339031-90-2
Molecular Formula C13H10ClFN2O3
Molecular Weight 296.68 g/mol
Synonyms Ethyl 5-Chloro-2-(4-fluorophenyl)-2,3-dihydropyridazine-3-one-6-carboxylate; 6-Carbethoxy-5-chloro-2-(4-fluorophenyl)-3(2H)-pyridazinone; 5-Chloro-2-(4-fluorophenyl)-6-(ethoxycarbonyl)-2,3-dihydropyridazin-3-one; Ethyl 5-chloro-2-(4-fluorophenyl)-3-oxo-2,3-dihydro-6-pyridazinecarboxylate; 339031-90-2; 2-(4-Fluorophenyl)-5-chloro-6-(ethoxycarbonyl)-2,3-dihydropyridazin-3-one
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Quality Control

Our Ethyl 5-Chloro-2,3-Dihydro-2-(4-Fluorophenyl)Pyridazin-3-One-6-Carboxylat is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC) Complies with ICH Q3C guidelines
Loss on Drying ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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