Description

n-(3-Acetylphenyl)-4-Fluorobenzenesulfonamide is a specialized sulfonamide derivative featuring both acetyl and fluorophenyl functional groups. This compound is a high-value synthetic intermediate prized for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel bioactive molecules, serving as a key building block in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A crucial building block in the research and synthesis of new chemical entities (NCEs) for drug discovery, particularly targeting enzymes and receptors where the sulfonamide moiety is pharmacologically relevant.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with potential therapeutic activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for further chemical transformations, including coupling reactions, amide formations, and the introduction of fluorinated aromatic systems into target molecules.
• Agrochemical Research: Potential intermediate in the development of advanced crop protection agents and herbicides, leveraging its unique fluorinated sulfonamide structure.
• Material Science Precursor: Can be utilized in the synthesis of specialized polymers or small molecules for advanced materials, such as ligands for catalysts or components in organic electronics.

Basic Information

Product Name	n-(3-Acetylphenyl)-4-Fluorobenzenesulfonamide
CAS No.	338966-27-1
Molecular Formula	C14H12FNO3S
Molecular Weight	293.31 g/mol
Synonyms	4-Fluoro-N-(3-acetylphenyl)benzenesulfonamide; 1-[3-[(4-Fluorophenyl)sulfonylamino]phenyl]ethanone; N-(3-Acetylphenyl)-4-fluorobenzenesulfonamide; 338966-27-1; 4-Fluoro-N-(3-acetylphenyl)benzenesulfonamide; p-Fluoro-N-(m-acetylphenyl)benzenesulfonamide; AKOS BRN-0791; 1-(3-{[(4-fluorophenyl)sulfonyl]amino}phenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our n-(3-Acetylphenyl)-4-Fluorobenzenesulfonamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.