Description

4-Iodo-2-Methoxyaniline is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a methoxy group, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aniline core.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for producing complex azo dyes and high-performance pigments requiring specific light-fastness and color properties.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to the reactive iodine atom.
• Chemical Research & Development: A valuable reagent for academic and industrial chemists exploring new synthetic methodologies and constructing molecular libraries.

Basic Information

Product Name	4-Iodo-2-Methoxyaniline
CAS No.	338454-80-1
Molecular Formula	C7H8INO
Molecular Weight	249.05 g/mol
Synonyms	2-Methoxy-4-iodoaniline; 4-Iodo-o-anisidine; 4-Iodo-2-methoxybenzenamine; 2-Amino-5-iodoanisole; 5-Iodo-2-aminoanisole; 4-Iodo-2-methoxyphenylamine; Benzenamine, 4-iodo-2-methoxy-
EINECS	Contact for details

Quality Control

Our 4-Iodo-2-Methoxyaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.