Description

3-(4-Methoxyphenyl)-4H-Pyrazol-4-One n-[4-(Trifluoromethyl)Phenyl]Hydrazone CAS NO 338414-26-9 is a high-purity, specialized heterocyclic organic compound featuring a pyrazolone core substituted with methoxyphenyl and trifluoromethylphenyl hydrazone groups. This molecular structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for research in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active ingredients.

Application

This compound serves as a critical precursor in several high-value chemical synthesis pathways. Its primary and potential applications include:

• Pharmaceutical Intermediate: Key building block in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Synthesis: Intermediate for developing novel pesticides or herbicides, leveraging the biological activity of the pyrazolone and trifluoromethyl motifs.
• Material Science Research: Used in the synthesis of organic ligands for metal-organic frameworks (MOFs) or as a monomer for specialized polymers.
• Biochemical Tool Compound: Serves as a research chemical in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Dye & Pigment Intermediate: Potential precursor in the synthesis of complex organic dyes and functional pigments due to its conjugated system.

Basic Information

Product Name	3-(4-Methoxyphenyl)-4H-Pyrazol-4-One n-[4-(Trifluoromethyl)Phenyl]Hydrazone
CAS No.	338414-26-9
Molecular Formula	C₁₇H₁₄F₃N₃O₂
Molecular Weight	349.31 g/mol
Synonyms	4H-Pyrazol-4-one, 3-(4-methoxyphenyl)-, 2-[4-(trifluoromethyl)phenyl]hydrazone; 3-(4-Methoxyphenyl)-1H-pyrazol-5(4H)-one (4-(trifluoromethyl)phenyl)hydrazone; 3-(p-Methoxyphenyl)-4H-pyrazol-4-one N-[4-(trifluoromethyl)phenyl]hydrazone; Pyrazolone Derivative CAS 338414-26-9; 4-(Trifluoromethyl)phenylhydrazone of 3-(4-Methoxyphenyl)-4H-pyrazol-4-one; Hydrazone Derivative of 3-(4-Methoxyphenyl)pyrazolone
EINECS	Contact for details

Quality Control

Our production of 3-(4-Methoxyphenyl)-4H-Pyrazol-4-One n-[4-(Trifluoromethyl)Phenyl]Hydrazone adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical R&D and synthesis work. All materials undergo comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment. We operate under a cGMP-compliant quality management system to meet the exacting standards of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.