Description

4-Chloro-2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-5-Piperazino-3(2H)-Pyridazinone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is essential for R&D chemists and process development teams in the pharmaceutical and agrochemical industries seeking to develop new compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its pyridazine and pyridine motifs for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways in academic and industrial research.
• Process Chemistry: Employed in route scouting and optimization for the scalable manufacturing of complex target molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	4-Chloro-2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-5-Piperazino-3(2H)-Pyridazinone
CAS No.	338399-95-4
Molecular Formula	C14H11Cl2F3N4O
Molecular Weight	379.17 g/mol
Synonyms	4-Chloro-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-5-(piperazin-1-yl)pyridazin-3(2H)-one; 4-Chloro-2-(3-chloro-5-trifluoromethyl-2-pyridyl)-5-piperazino-3(2H)-pyridazinone; CAS 338399-95-4; 5-Piperazino-4-chloro-2-(3-chloro-5-trifluoromethyl-2-pyridyl)-3(2H)-pyridazinone; 2H-Pyridazin-3-one, 4-chloro-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-5-(1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-5-Piperazino-3(2H)-Pyridazinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.