Description

4-Chloro-2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-5-[(2-Hydroxyethyl)(Methyl)Amino]-3(2H)-Pyridazinone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is essential for research institutions and manufacturers engaged in the development of agrochemicals and specialty fine chemicals, where precise chemical functionality is critical.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially in oncology and central nervous system (CNS) research.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides and pesticides with specific mode-of-action targets.
• Chemical Biology Probe: Used in academic and industrial R&D to study enzyme inhibition and receptor-ligand interactions due to its specific pyridazinone and pyridine motifs.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing complex, high-value specialty molecules.

Basic Information

Product Name	4-Chloro-2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-5-[(2-Hydroxyethyl)(Methyl)Amino]-3(2H)-Pyridazinone
CAS No.	338399-91-0
Molecular Formula	C13H11Cl2F3N4O2
Molecular Weight	383.16 g/mol
Synonyms	4-Chloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-[(2-hydroxyethyl)(methyl)amino]pyridazin-3(2H)-one; 5-[(2-Hydroxyethyl)(methyl)amino]-4-chloro-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-3(2H)-pyridazinone; CAS 338399-91-0; Pyridazinone derivative intermediate; Chloro-trifluoromethyl pyridinyl pyridazinone
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-5-[(2-Hydroxyethyl)(Methyl)Amino]-3(2H)-Pyridazinone adheres to stringent quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific research or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.