Description

[4-(4-Methoxy-Phenyl)-2,2-Dimethyl-Tetrahydro-Pyran-4-Yl]-Acetic Acid is a high-purity synthetic intermediate characterized by its unique tetrahydro-pyran ring structure substituted with a methoxyphenyl group. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, offering a defined chiral center and functional handles for further chemical elaboration. It is primarily needed by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced material science projects.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural complexity can contribute to novel modes of action.
• Organic Chemistry Research: Acts as a versatile scaffold in academic and industrial R&D for studying cyclization reactions, asymmetric synthesis, and structure-activity relationships (SAR).
• Material Science Precursor: Potential use in the synthesis of specialty polymers or liquid crystals due to its rigid, aromatic-containing core structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	[4-(4-Methoxy-Phenyl)-2,2-Dimethyl-Tetrahydro-Pyran-4-Yl]-Acetic Acid
CAS No.	337486-10-9
Molecular Formula	C₁₆H₂₂O₄
Molecular Weight	278.34 g/mol
Synonyms	4-(4-Methoxyphenyl)-2,2-dimethyltetrahydro-2H-pyran-4-acetic acid; (4-(4-Methoxyphenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl)acetic acid; 2,2-Dimethyl-4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-acetic acid; 4-(4-Methoxy-phenyl)-2,2-dimethyl-tetrahydro-pyran-4-yl-acetic acid; 337486-10-9; Acetic acid, [4-(4-methoxyphenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl]-
EINECS	Contact for details

Quality Control

Our [4-(4-Methoxy-Phenyl)-2,2-Dimethyl-Tetrahydro-Pyran-4-Yl]-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.