Description

Tetrahydro-Pyridazine-1,2,3-Tricarboxylic Acid 1,2-Di-tert-Butyl Ester 3-Ethyl Ester is a high-purity, multi-functional organic building block designed for advanced synthetic chemistry. This compound is valued for its role as a key chiral intermediate and protecting group scaffold in the synthesis of complex pharmaceutical molecules and fine chemicals. It is primarily sought by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting novel therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, leveraging its complex heterocyclic structure.
• Fine Chemical Production: Serves as a versatile building block for synthesizing specialty chemicals, dyes, and functional materials requiring specific stereochemistry.
• Academic & Industrial Research: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.
• Peptidomimetic & Protease Inhibitor Scaffold: Its structure is applicable in designing peptide analogs and enzyme inhibitors for biochemical research.

Basic Information

Product Name	Tetrahydro-Pyridazine-1,2,3-Tricarboxylic Acid 1,2-Di-tert-Butyl Ester 3-Ethyl Ester
CAS No.	336817-83-5
Molecular Formula	C18H30N2O6
Molecular Weight	370.44 g/mol
Synonyms	1,2,3,6-Tetrahydro-1,2,3-pyridazinetricarboxylic acid, 1,2-bis(1,1-dimethylethyl) 3-ethyl ester; 1,2-Di-tert-butyl 3-ethyl 1,2,3,6-tetrahydropyridazine-1,2,3-tricarboxylate; Ethyl 1,2-di-tert-butyl 1,2,3,6-tetrahydropyridazine-1,2,3-tricarboxylate; 3-Ethyl 1,2-di-tert-butyl 1,2,3,6-tetrahydropyridazine-1,2,3-tricarboxylate; Tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-ethyl ester; 336817-83-5; 1,2,3,6-Tetrahydropyridazine-1,2,3-tricarboxylic acid tri-tert-butyl ethyl ester (mixed isomer).
EINECS	Contact for details

Quality Control

Our production of Tetrahydro-Pyridazine-1,2,3-Tricarboxylic Acid 1,2-Di-tert-Butyl Ester 3-Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.