Description

(R)-n-(4-Chlorobenzylidene)-2-Methylpropane-2-Sulfinamide CAS NO 336105-23-8 is a high-purity chiral sulfinamide building block, specifically the (R)-enantiomer, which serves as a critical intermediate in asymmetric synthesis. Its value lies in its ability to induce chirality and control stereochemistry in the production of complex pharmaceutical molecules and advanced agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral auxiliaries and ligands.

Application

• As a chiral auxiliary in the asymmetric synthesis of active pharmaceutical ingredients (APIs).
• Key intermediate for constructing complex molecules in medicinal chemistry and drug discovery programs.
• Building block for the development of novel ligands used in catalytic asymmetric reactions.
• Precursor in the synthesis of agrochemicals requiring specific stereochemistry for enhanced activity.
• Research reagent for academic and industrial studies in organic and organometallic chemistry.
• Starting material for the preparation of other enantiomerically pure sulfinamide derivatives.

Basic Information

Product Name	(R)-n-(4-Chlorobenzylidene)-2-Methylpropane-2-Sulfinamide
CAS No.	336105-23-8
Molecular Formula	C11H14ClNOS
Molecular Weight	243.75 g/mol
Synonyms	(R)-N-[(4-Chlorophenyl)methylene]-2-methylpropane-2-sulfinamide; (R)-p-Chlorobenzylidene-tert-butylsulfinamide; (R)-N-(4-Chlorobenzylidene)-2-methyl-2-propanesulfinamide; (R)-tert-Butanesulfinamide, N-[(4-chlorophenyl)methylene]-; (R)-N-(4-Chlorobenzylidene) tert-butylsulfinamide; (R)-4-Chlorobenzaldehyde tert-butylsulfinyl imine; (R)-N-(4-Chlorobenzylidene)-2-methylpropane-2-sulfinamide
EINECS	Contact for details

Quality Control

Our (R)-n-(4-Chlorobenzylidene)-2-Methylpropane-2-Sulfinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent quality and traceability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.