Description

2,4-Dimethoxy-n-((4-Phenyl-Tetrahydro-2H-Pyran-4-Yl)Methyl)Benzamide is a sophisticated organic compound featuring a benzamide core linked to a substituted tetrahydropyran moiety. This molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active compounds. The compound's specific stereochemistry and functional groups are critical for modulating biological activity and pharmacokinetic properties in drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or other therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Agrochemical Research: Acts as an intermediate in the development of new active ingredients for crop protection products, leveraging its complex heterocyclic structure.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale production of complex organic molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific chemical entity.

Basic Information

Product Name	2,4-Dimethoxy-n-((4-Phenyl-Tetrahydro-2H-Pyran-4-Yl)Methyl)Benzamide
CAS No.	332391-86-3
Molecular Formula	C21H25NO4
Molecular Weight	355.43 g/mol
Synonyms	N-[(4-Phenyloxan-4-yl)methyl]-2,4-dimethoxybenzamide; 2,4-Dimethoxy-N-{[4-phenyl(tetrahydro-2H-pyran-4-yl)]methyl}benzamide; Benzamide, N-[(4-phenyltetrahydro-2H-pyran-4-yl)methyl]-2,4-dimethoxy-; 2,4-Dimethoxybenzoic acid (4-phenyltetrahydropyran-4-yl)methylamide; 4-Phenyltetrahydropyran-4-carboxamide derivative
EINECS	Contact for details

Quality Control

Our 2,4-Dimethoxy-n-((4-Phenyl-Tetrahydro-2H-Pyran-4-Yl)Methyl)Benzamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate supply, supporting your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.