Description

Ethyl 2-Amino-7-Hydroxy-4-(Pyridin-3-Yl)-4H-Chromene-3-Carboxylate is a high-purity, functionalized chromene derivative that serves as a critical synthetic intermediate. This compound is valued for its unique molecular scaffold, which combines a chromene core with amino, hydroxy, and pyridyl functionalities, enabling diverse chemical modifications. It is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for the synthesis of novel heterocyclic compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for creating combinatorial libraries and exploring structure-activity relationships (SAR) in academic and industrial R&D.
• Organic Synthesis: Serves as a precursor for synthesizing more complex fused heterocyclic systems due to its reactive amino and hydroxyl groups.
• Chemical Biology Probes: Utilized in the development of fluorescent probes or enzyme inhibitors for biochemical assays and diagnostic research.
• Material Science Precursor: Potential intermediate in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Product Name	Ethyl 2-Amino-7-Hydroxy-4-(Pyridin-3-Yl)-4H-Chromene-3-Carboxylate
CAS No.	332164-34-8
Molecular Formula	C₁₇H₁₆N₂O₄
Molecular Weight	312.32 g/mol
Synonyms	2-Amino-7-hydroxy-4-(3-pyridinyl)-4H-1-benzopyran-3-carboxylic acid ethyl ester; Ethyl 2-amino-7-hydroxy-4-(3-pyridyl)-4H-chromene-3-carboxylate; 4H-Chromene-3-carboxylic acid, 2-amino-7-hydroxy-4-(3-pyridinyl)-, ethyl ester; 3-Pyridinechromene derivative; 7-Hydroxy-2-amino-4-(pyridin-3-yl)chromene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-7-Hydroxy-4-(Pyridin-3-Yl)-4H-Chromene-3-Carboxylate is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.