Description

4-(Tributylstannyl)Pyrimidine is a specialized organotin reagent featuring a pyrimidine heterocycle, a key intermediate in modern synthetic organic chemistry. Its core value lies in enabling efficient Stille cross-coupling reactions, a powerful method for forming carbon-carbon bonds under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise functionalization of complex molecular architectures.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing pyrimidine-based nucleoside analogs and other heterocyclic drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the pyrimidine moiety for enhanced biological activity.
• Material Science Research: Serves as a building block for creating functional organic materials, including ligands for catalysis, organic semiconductors, and liquid crystals.
• Stille Cross-Coupling Reactions: Acts as a versatile organostannane coupling partner for introducing the pyrimidine group into complex molecules with high selectivity and yield.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A key reagent for fine chemical and custom synthesis houses serving the R&D and pilot-scale production needs of global clients.

Basic Information

Product Name	4-(Tributylstannyl)Pyrimidine
CAS No.	332133-92-3
Molecular Formula	C16H30N2Sn
Molecular Weight	377.13 g/mol
Synonyms	4-Tributylstannylpyrimidine; Pyrimidine, 4-(tributylstannyl)-; Tributyl(4-pyrimidinyl)stannane; 4-Pyrimidinyltributyltin; 4-(Tributyltin)pyrimidine; Stannane, tributyl(4-pyrimidinyl)-; (4-Pyrimidinyl)tributylstannane
EINECS	Contact for details

Quality Control

Every batch of 4-(Tributylstannyl)Pyrimidine undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system is designed to meet the stringent requirements of research and industrial-scale applications. Certificates of Analysis (COA) detailing specific batch results for purity (by NMR, HPLC), tin content, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Tin (Sn) Content	30.0 - 32.0 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.