Description

2-Amino-4-(sec-Butyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is a high-value, multifunctional chromene derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular scaffold, featuring both amino and nitrile functional groups, makes it an essential building block for constructing complex heterocyclic compounds. This compound is primarily sought after by research institutions and pharmaceutical development companies for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used as a core scaffold for developing new generation pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including multicomponent reactions and heterocycle construction.
• Dye & Pigment Synthesis: Intermediate for creating novel chromene-based dyes and functional colorants with specific optical properties.
• Chemical Biology Probes: Used to develop molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	2-Amino-4-(sec-Butyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile
CAS No.	332045-36-0
Molecular Formula	C₁₆H₂₂N₂O₂
Molecular Weight	274.36 g/mol
Synonyms	2-Amino-4-(1-methylpropyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; 4H-Chromene-3-carbonitrile, 2-amino-4-(1-methylpropyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-; 2-Amino-4-(sec-butyl)-7,7-dimethyl-5-oxo-4H,5H,6H,7H,8H-chromene-3-carbonitrile; 3-Cyano-2-amino-4-(sec-butyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene; Tetrahydrochromene Carbonitrile Derivative; Chromene Nitrile Intermediate
EINECS	Contact for details

Quality Control

Every batch of our 2-Amino-4-(sec-Butyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all shipments. Our quality protocols are designed to support regulatory filings in pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.