Description

4-(5-Bromo-2-Methylphenylsulfonyl)Morpholine is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its role as a key building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for their innovative projects.

Application

This morpholine sulfonamide derivative serves as a versatile intermediate in several high-value industrial sectors. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its bromo and sulfonyl functional groups.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid aromatic and polar sulfonamide structure.
• Chemical Biology & Proteomics: Acts as a scaffold or linker in the design of chemical probes and enzyme inhibitors for target validation and mechanistic studies.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular fragment.

Basic Information

Product Name	4-(5-Bromo-2-Methylphenylsulfonyl)Morpholine
CAS No.	330827-25-3
Molecular Formula	C11H14BrNO3S
Molecular Weight	320.21 g/mol
Synonyms	4-[(5-Bromo-2-methylphenyl)sulfonyl]morpholine; Morpholine, 4-[(5-bromo-2-methylphenyl)sulfonyl]-; 5-Bromo-2-methylbenzenesulfonyl morpholine; 4-(5-Bromo-o-tolylsulfonyl)morpholine; 330827-25-3; 4-(5-Bromo-2-methylbenzenesulfonyl)morpholine
EINECS	Contact for details

Quality Control

Our 4-(5-Bromo-2-Methylphenylsulfonyl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements of our R&D and manufacturing clients. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with every shipment to guarantee supply reliability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.