Description

6-Chloro-1,2,4-triazolo[4,3-b]pyridazine-3-carboxylic acid is a heterocyclic carboxylic acid derivative that serves as a versatile and high-value synthetic building block in advanced organic chemistry. Its unique fused triazolopyridazine scaffold makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Building block for developing new generations of herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of advanced organic electronic materials and photoactive compounds.
• Academic & Contract Research: Essential reagent for methodological studies in heterocyclic chemistry and for creating specialized compound libraries for high-throughput screening.
• Chemical Biology: Serves as a core structure for designing molecular probes and enzyme inhibitors to study biological pathways.

Basic Information

Product Name	6-Chloro-1,2,4-triazolo[4,3-b]pyridazine-3-carboxylic Acid
CAS No.	330440-43-2
Molecular Formula	C6H3ClN4O2
Molecular Weight	198.57 g/mol
Synonyms	6-Chloro-1,2,4-triazolo[4,3-b]pyridazine-3-carboxylic acid; 6-Chloro-[1,2,4]triazolo[4,3-b]pyridazine-3-carboxylic acid; 330440-43-2; 6-Chloro-1H-[1,2,4]triazolo[4,3-b]pyridazine-3-carboxylic acid; 6-Chloro-1,2,4-triazolo[4,3-b]pyridazine-3-carboxylic acid; 3-Carboxy-6-chloro-1,2,4-triazolo[4,3-b]pyridazine
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-1,2,4-triazolo[4,3-b]pyridazine-3-carboxylic acid adheres to strict in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identification. Our quality system is designed to support cGMP-compliant applications for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.