Description

2,2-Dimethyl-4H-1,3-Dioxin-5-Yl Trifluoromethanesulfonate is a specialized, high-value triflate ester derivative used as a key synthetic intermediate. This compound is critical for introducing the 2,2-dimethyl-1,3-dioxin moiety into target molecules, enabling advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds containing protected diol or masked carbonyl functionalities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the dioxin structure imparts specific biological activity or stability.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Polymer & Material Science: Employed in the synthesis of functional monomers and specialty polymers, contributing to materials with tailored thermal or optical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry, including studies on nucleophilic substitution and protecting group strategies.

Basic Information

Product Name	2,2-Dimethyl-4H-1,3-Dioxin-5-Yl Trifluoromethanesulfonate
CAS No.	330435-58-0
Molecular Formula	C8H9F3O5S
Molecular Weight	274.21 g/mol
Synonyms	5-(Trifluoromethanesulfonyloxy)-2,2-dimethyl-4H-1,3-dioxine; 2,2-Dimethyl-5-trifluoromethanesulfonyloxy-4H-1,3-dioxine; 2,2-Dimethyl-1,3-dioxin-5-yl triflate; 5-Triflyloxy-2,2-dimethyl-4H-1,3-dioxin; 330435-58-0; Dioxinyl Triflate Ester
EINECS	Contact for details

Quality Control

Our production of 2,2-Dimethyl-4H-1,3-Dioxin-5-Yl Trifluoromethanesulfonate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We maintain GMP-compliant documentation practices for traceability, and specifications can be aligned with customer-specific requirements for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.