Description

2-[(3-Chloro-4-Fluoro-Phenylamino)-Methyl]-Phenol is a specialized organic intermediate featuring a phenolic core substituted with a chlorinated and fluorinated anilino-methyl group. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, leveraging its halogenated aromatic structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the design of novel chelating ligands for metal catalysts used in asymmetric synthesis.
• Academic & Industrial R&D: A versatile scaffold for medicinal chemistry programs and structure-activity relationship (SAR) studies in various life science fields.

Basic Information

Item	Detail
Product Name	2-[(3-Chloro-4-Fluoro-Phenylamino)-Methyl]-Phenol
CAS No.	329779-41-1
Molecular Formula	C13H11ClFNO
Molecular Weight	251.68 g/mol
Synonyms	2-[(3-Chloro-4-fluoroanilino)methyl]phenol; Phenol, 2-[(3-chloro-4-fluorophenylamino)methyl]-; 3-Chloro-4-fluoro-N-(2-hydroxybenzyl)aniline; (2-Hydroxybenzyl)(3-chloro-4-fluorophenyl)amine; 329779-41-1; 2-[(3-Chloro-4-fluoro-phenylamino)-methyl]-phenol
EINECS	Contact for details

Quality Control

Our 2-[(3-Chloro-4-Fluoro-Phenylamino)-Methyl]-Phenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon) to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.