Description

Benzamide, n-[[[(6,11-Dihydro-5H-Dibenz[B,E]Azepin-6-Yl)Methyl]Amino]Thioxomethyl]- is a specialized organic compound belonging to the dibenzazepine class, serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its precise molecular architecture makes it a valuable building block for developing active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders. This high-purity intermediate is essential for research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of novel tricyclic antidepressant and antipsychotic drug candidates.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new CNS-active compounds.
• API Synthesis: Employed in multi-step synthesis routes for complex molecules targeting specific neurotransmitter receptors.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Preclinical Studies: Utilized in the synthesis of compounds for pharmacological evaluation and toxicology assessments.

Basic Information

Product Name	Benzamide, n-[[[(6,11-Dihydro-5H-Dibenz[B,E]Azepin-6-Yl)Methyl]Amino]Thioxomethyl]-
CAS No.	329038-65-5
Molecular Formula	C23H21N3OS
Molecular Weight	387.50 g/mol
Synonyms	N-({[(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-yl)methyl]carbamothioyl})benzamide; 6-({[(Benzoylamino)thioxomethyl]amino}methyl)-5,6-dihydro-11H-dibenzo[b,e]azepine; Dibenzazepine carbothioamide derivative; (6,11-Dihydro-5H-dibenzo[b,e]azepin-6-yl)methyl thiourea benzoyl derivative; CAS 329038-65-5
EINECS	Contact for details

Quality Control

Our Benzamide, n-[[[(6,11-Dihydro-5H-Dibenz[B,E]Azepin-6-Yl)Methyl]Amino]Thioxomethyl]- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity suitable for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.