Description

4-(3-Bromophenyl)Tetrahydro-2H-Pyran-4-Carboxamide is a high-purity brominated heterocyclic carboxamide building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular scaffold, which serves as a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its bromophenyl and carboxamide functionalities.
• Material Science: Serves as a monomer or precursor for specialty polymers and liquid crystals with specific optical or electronic properties.
• Chemical Synthesis: Acts as a versatile synthon for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive bromine atom.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and library synthesis for high-throughput screening.

Basic Information

Product Name	4-(3-Bromophenyl)Tetrahydro-2H-Pyran-4-Carboxamide
CAS No.	329025-26-5
Molecular Formula	C12H14BrNO2
Molecular Weight	284.15 g/mol
Synonyms	4-(3-Bromophenyl)tetrahydro-2H-pyran-4-carboxamide; 4-(3-Bromophenyl)oxane-4-carboxamide; 4-Carbamoyl-4-(3-bromophenyl)tetrahydropyran; 3-Bromo-α,α-pentamethylenebenzeneacetamide; Tetrahydro-4-(3-bromobenzoyl)-2H-pyran-4-carboxamide (related form); 329025-26-5; 4-(3-Bromophenyl)tetrahydropyran-4-carboxamide
EINECS	Contact for details

Quality Control

Our 4-(3-Bromophenyl)Tetrahydro-2H-Pyran-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.