Description

(4R,5R)-(-)-2,2-Dimethyl-Tetraphenyl-1,3-Dioxolane-4,5-Dimethanolato[1,2-Bis(Dimethoxy)Ethane]Titanium(IV) Dic is a highly specialized, chiral titanium-based organometallic complex. This compound matters as a highly effective and enantioselective catalyst, enabling precise control over stereochemistry in advanced synthetic transformations. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of chiral intermediates and active ingredients.

Application

• Asymmetric Catalysis: A key catalyst for enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions, such as Diels-Alder, aldol, and epoxidation reactions.
• Pharmaceutical Intermediate Synthesis: Critical for the production of single-enantiomer drug candidates and active pharmaceutical ingredients (APIs) where chirality is essential for biological activity.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and pesticides to enhance efficacy and reduce environmental impact.
• Fine Chemical Production: Enables the manufacture of high-value, optically pure flavors, fragrances, and specialty materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis research.
• Polymer Science: Potential application in the stereoselective polymerization of olefins for creating polymers with specific tacticity.

Basic Information

Product Name	(4R,5R)-(-)-2,2-Dimethyl-Tetraphenyl-1,3-Dioxolane-4,5-Dimethanolato[1,2-Bis(Dimethoxy)Ethane]Titanium(IV) Dic
CAS No.	328123-04-2
Molecular Formula	C44H48O6Ti
Molecular Weight	696.74 g/mol
Synonyms	Titanium(IV) (R,R)-TADDOLate Complex; (R,R)-TADDOL-Titanium Dichloride Complex; (4R,5R)-TADDOL-TiCl2; (R,R)-TADDOL-TiCl2; Titanium TADDOLate Catalyst; (R,R)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanolato titanium dichloride; (R,R)-TADDOL Titanium Dichloride; TADDOL-Ti Catalyst
EINECS	Contact for details

Quality Control

Our (4R,5R)-TADDOL-Titanium Dichloride complex is produced under controlled conditions to ensure batch-to-batch consistency and high catalytic activity. Each lot undergoes rigorous quality testing, including chiral purity analysis and assay determination, to meet the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool place. This material is hygroscopic and moisture-sensitive; ensure containers are sealed immediately after use to prevent decomposition.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.