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n-(6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline-2-Carbonothioyl)Benzamide CAS NO 328022-63-5


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CAS No.:328022-63-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline-2-Carbonothioyl)Benzamide is a specialized thiourea derivative with a complex heterocyclic structure, serving as a critical synthetic intermediate and research chemical. This compound matters for its role in facilitating advanced organic synthesis, particularly in the development of novel pharmacologically active molecules. Pharmaceutical R&D laboratories, agrochemical innovators, and academic institutions engaged in medicinal chemistry need this high-purity building block for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting neurological or cardiovascular pathways.
  • Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
  • Agrochemical Development: Serves as an intermediate in the research and synthesis of novel pesticides or herbicides with specific biological activity.
  • Chemical Biology Probe: Utilized in the development of molecular probes to study enzyme function or protein-ligand interactions due to its thiourea moiety.
  • Organic Synthesis Reagent: Acts as a versatile reagent for introducing the tetrahydroisoquinoline-thiobenzamide functional group into more complex molecules.
  • Academic & Institutional Research: Employed in university and government labs for fundamental research in heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name n-(6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline-2-Carbonothioyl)Benzamide
CAS No. 328022-63-5
Molecular Formula C19H20N2O3S
Molecular Weight 356.44 g/mol
Synonyms Benzamide, N-[(6,7-dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl)carbonothioyl]-; 1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-phenylthiourea; N-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbothioyl)benzamide; 328022-63-5; 2-Benzoylthiocarbamoyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-2-(phenylcarbamothioyl)-1,2,3,4-tetrahydroisoquinoline
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Quality Control

Our n-(6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline-2-Carbonothioyl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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