Description

1-[(2,5-Dichlorophenyl)Sulfonyl]Pyrrolidine is a specialized organosulfur compound featuring a pyrrolidine ring linked to a dichlorophenylsulfonyl group, making it a valuable building block in advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where its unique sulfonamide structure can impart specific biological activity or serve as a crucial synthetic handle. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the dichlorophenyl and sulfonamide motifs are common in bioactive molecules.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function or protein-protein interactions, leveraging its potential as a sulfonamide-based inhibitor scaffold.
• Material Science Research: Investigated as a monomer or additive in the creation of specialized polymers with specific thermal or chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes for complex target molecules.

Basic Information

Product Name	1-[(2,5-Dichlorophenyl)Sulfonyl]Pyrrolidine
CAS No.	326898-65-1
Molecular Formula	C10H11Cl2NO2S
Molecular Weight	280.17 g/mol
Synonyms	N-[(2,5-Dichlorophenyl)sulfonyl]pyrrolidine; Pyrrolidine, 1-[(2,5-dichlorophenyl)sulfonyl]-; 2,5-Dichloro-N-(pyrrolidin-1-ylsulfonyl)aniline; 1-(2,5-Dichlorobenzenesulfonyl)pyrrolidine; (2,5-Dichlorophenyl)(pyrrolidin-1-yl)sulfone; 326898-65-1; 1-(2,5-Dichlorophenylsulfonyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 1-[(2,5-Dichlorophenyl)Sulfonyl]Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.