Description

6-Hydrazinyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine is a high-value, heterocyclic organic compound featuring a fused triazolopyridazine core functionalized with hydrazinyl and trifluoromethyl groups. This unique structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. The compound is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and purity for demanding applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the triazolopyridazine scaffold.
• Medicinal Chemistry: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable hydrazine moiety and fluorine-containing group.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with unique thermal or optical properties.

Basic Information

Product Name	6-Hydrazinyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine
CAS No.	325990-23-6
Molecular Formula	C6H5F3N6
Molecular Weight	218.14 g/mol
Synonyms	3-(Trifluoromethyl)-6-hydrazinyl-[1,2,4]triazolo[4,3-b]pyridazine; 6-Hydrazinyl-3-(trifluoromethyl)-1,2,4-triazolo[4,3-b]pyridazine; [1,2,4]Triazolo[4,3-b]pyridazine, 6-hydrazinyl-3-(trifluoromethyl)-; 6-Hydrazino-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine; 325990-23-6; 3-Trifluoromethyl-6-hydrazinyl-[1,2,4]triazolo[4,3-b]pyridazine
EINECS	Contact for details

Quality Control

Every batch of 6-Hydrazinyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and other high-purity applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.