Description

Cyclopenta[C]Pyran-4-Carboxylic Acid, 1-(β-D-Glucopyranosyloxy)-1,4A,5,6-Tetrahydro-7-(Hydroxymethyl)-, (1S,4As)- is a complex, high-purity glycosylated cyclopentapyran derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block and intermediate, offering a unique fused-ring scaffold with multiple functional handles for constructing biologically active molecules. It is primarily needed by research institutions and pharmaceutical development teams working on novel therapeutic agents, particularly in the areas of glycosidase inhibitors, antiviral compounds, and natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates targeting metabolic and viral diseases.
• Glycosidase Inhibitor Research: Used as a core structure for developing and testing new classes of enzyme inhibitors due to its glucopyranosyl moiety.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Bioconjugation & Probe Development: The carboxylic acid and hydroxyl groups enable conjugation to carriers, labels, or other molecules for biochemical studies.
• Natural Product Synthesis: Acts as an advanced intermediate in the total or semi-synthesis of complex natural products containing similar fused-ring glycoside architectures.
• Chemical Biology Tool: Utilized to investigate carbohydrate-protein interactions and glycosylation pathways in biological systems.

Basic Information

Product Name	Cyclopenta[C]Pyran-4-Carboxylic Acid, 1-(β-D-Glucopyranosyloxy)-1,4A,5,6-Tetrahydro-7-(Hydroxymethyl)-, (1S,4As)-
CAS No.	325798-51-4
Molecular Formula	C₁₆H₂₂O₁₀
Molecular Weight	374.34 g/mol
Synonyms	(1S,4aS)-1-(β-D-Glucopyranosyloxy)-1,4a,5,6-tetrahydro-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid; 1-O-(β-D-Glucopyranosyl)-1,4a,5,6-tetrahydro-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid (1S,4aS)-isomer; Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6-tetrahydro-7-(hydroxymethyl)-, (1S,4aS)-; Glycosylated cyclopentapyran carboxylic acid; CAS 325798-51-4
EINECS	Contact for details

Quality Control

Our Cyclopenta[C]Pyran-4-Carboxylic Acid derivative is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and MS for identity verification. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere. The material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.