Description

(5E)-5-[(2,4-Diphenyl-4H-Chromen-3-Yl)Methylidene]-2-Thioxo-1,3-Thiazolidin-4-One CAS NO 325730-12-9 is a high-purity, synthetic heterocyclic compound featuring a chromene core fused with a rhodanine (2-thioxothiazolidin-4-one) moiety. This specific molecular architecture makes it a valuable advanced intermediate or building block for research and development in medicinal chemistry and material science. It is primarily sought after by pharmaceutical R&D laboratories and specialty chemical manufacturers for creating novel compounds with targeted biological or photophysical properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential therapeutic agents, particularly for research into anti-inflammatory, antimicrobial, or anticancer compounds.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its rhodanine-chromene hybrid structure.
• Organic Electronic Material Precursor: Investigated as a building block for organic semiconductors or light-emitting materials, leveraging its conjugated π-system.
• Dye and Pigment Synthesis: Functions as an intermediate in the development of specialized dyes and pigments, where its chromophore contributes to color properties.
• Biochemical Probe Development: Utilized in designing molecular probes for studying enzyme inhibition or cellular processes.
• Academic and Industrial R&D: Employed in fundamental chemical research and the development of novel synthetic methodologies.

Basic Information

Product Name	(5E)-5-[(2,4-Diphenyl-4H-Chromen-3-Yl)Methylidene]-2-Thioxo-1,3-Thiazolidin-4-One
CAS No.	325730-12-9
Molecular Formula	C25H15NO2S2
Molecular Weight	425.52 g/mol
Synonyms	5-[(2,4-Diphenyl-4H-chromen-3-yl)methylene]-2-thioxo-1,3-thiazolidin-4-one; (5E)-5-[(2,4-Diphenyl-4H-1-benzopyran-3-yl)methylene]-2-sulfanylidene-1,3-thiazolidin-4-one; 4H-1-Benzopyran-4-one, 5-[(2,4-diphenyl-4H-1-benzopyran-3-yl)methylene]-2-thioxo-1,3-thiazolidin-; Rhodanine-chromene derivative; Chromene-rhodanine hybrid; 2,4-Diphenyl-3-[(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-4H-chromene
EINECS	Contact for details

Quality Control

Our production of (5E)-5-[(2,4-Diphenyl-4H-Chromen-3-Yl)Methylidene]-2-Thioxo-1,3-Thiazolidin-4-One adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.