Description

n-Benzyl-2,3,5,6-Tetramethylbenzenesulfonamide is a specialized sulfonamide derivative characterized by its unique sterically hindered aromatic structure. This compound serves as a valuable building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and functional materials. It is primarily needed by research institutions, pharmaceutical R&D labs, and fine chemical manufacturers engaged in creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of new drug candidates, particularly those requiring sulfonamide pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or additive in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Potential use as a labeling reagent or probe due to its reactive sulfonamide group and benzyl moiety.
• Catalyst & Ligand Development: The tetramethylbenzene scaffold can be utilized to create sterically demanding ligands for transition metal catalysis.
• Academic & Industrial Research: A versatile reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	n-Benzyl-2,3,5,6-Tetramethylbenzenesulfonamide
CAS No.	321704-17-0
Molecular Formula	C₁₉H₂₅NO₂S
Molecular Weight	331.47 g/mol
Synonyms	N-Benzyl-2,3,5,6-tetramethylbenzenesulfonamide; Benzenesulfonamide, N-benzyl-2,3,5,6-tetramethyl-; N-Benzylpentamethylbenzenesulfonamide; 2,3,5,6-Tetramethyl-N-(phenylmethyl)benzenesulfonamide; Durenylsulfonamide, N-benzyl-; Benzyl durenyl sulfonamide; BTSA (abbreviation in some contexts); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our n-Benzyl-2,3,5,6-Tetramethylbenzenesulfonamide is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.