Description

Cyclohexanone, 2-Ethoxy-3-Hydroxy-3,5,5-Trimethyl-, Oxime, (1E,2R,3R)-Rel- (9Ci) is a high-purity, stereochemically defined oxime derivative of a substituted cyclohexanone. This compound is a critical advanced pharmaceutical intermediate (API) and a valuable building block in fine chemical synthesis, prized for its specific stereochemistry and functional groups. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors for the development and manufacture of complex, high-value molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators where specific stereochemistry is crucial for bioactivity.
• Fine Chemical Manufacturing: Serves as a precursor for dyes, pigments, photoinitiators, and other performance chemicals requiring a defined cyclohexanone-oxime core structure.
• Research & Development: Employed in academic and industrial R&D for methodological studies in asymmetric synthesis, oxime chemistry, and the development of new catalytic processes.
• Ligand and Catalyst Preparation: Utilized as a starting material for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.

Basic Information

Product Name	Cyclohexanone, 2-Ethoxy-3-Hydroxy-3,5,5-Trimethyl-, Oxime, (1E,2R,3R)-Rel- (9Ci)
CAS No.	318479-78-6
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	(1E,2R,3R)-2-Ethoxy-3-hydroxy-3,5,5-trimethylcyclohexanone oxime; rel-(1E,2R,3R)-2-Ethoxy-3-hydroxy-3,5,5-trimethylcyclohexanone oxime; 3,5,5-Trimethyl-2-ethoxy-3-hydroxycyclohexanone oxime; (1E,2R,3R)-rel-2-Ethoxy-3-hydroxy-3,5,5-trimethylcyclohexan-1-one oxime; Cyclohexanone oxime, 2-ethoxy-3-hydroxy-3,5,5-trimethyl-, (1E,2R,3R)-rel-; 2-Ethoxy-3-hydroxy-3,5,5-trimethylcyclohexanone oxime (isomer not specified); A potential advanced synthetic intermediate for Cariprazine-related chemistry.
EINECS	Contact for details

Quality Control

Our production of Cyclohexanone, 2-Ethoxy-3-Hydroxy-3,5,5-Trimethyl-, Oxime, (1E,2R,3R)-Rel- (9Ci) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral assay, NMR, and IR for structural confirmation, to ensure identity, strength, and compositional integrity. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our quality commitment supports compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (for specified isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.