Description

1-Bromo-3-(Chloromethyl)-5-Nitrobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromo, chloromethyl, and nitro functional groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those with complex aromatic backbones.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the nitro and halogen substituents are essential for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for metal catalysis and organocatalysts.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing nitro- and halogen-substituted dyes and organic pigments.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services targeting niche and high-value compounds.

Basic Information

Product Name	1-Bromo-3-(Chloromethyl)-5-Nitrobenzene
CAS No.	318261-49-3
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	3-Bromo-5-nitrobenzyl chloride; 5-Nitro-3-bromobenzyl chloride; 1-Bromo-3-(chloromethyl)-5-nitrobenzene; (3-Bromo-5-nitrophenyl)methyl chloride; Benzene, 1-bromo-3-(chloromethyl)-5-nitro-; 3-Bromo-5-nitrobenzylchloride
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(Chloromethyl)-5-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive chloromethyl group, it should be stored separately from strong bases and nucleophiles.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.