Description

Methyl 2-Amino-7,7-Dimethyl-4-(2-Nitrophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carboxylate is a high-purity, synthetically valuable chromene derivative, serving as a critical advanced intermediate in modern organic synthesis. Its complex molecular architecture, featuring fused chromene and tetrahydroquinoline-like structures with amino, nitro, and ester functionalities, makes it indispensable for constructing sophisticated heterocyclic compounds. This compound is primarily sought by research institutions and pharmaceutical R&D departments for developing novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Heterocyclic Compound Synthesis: Serves as a precursor for the preparation of complex polycyclic frameworks, including various fused chromene and quinoline derivatives.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides due to its bioactive core structure.
• Material Science Precursor: Investigated for the synthesis of organic semiconductors, dyes, or photoactive materials owing to its conjugated system and functional groups.

Basic Information

Product Name	Methyl 2-Amino-7,7-Dimethyl-4-(2-Nitrophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carboxylate
CAS No.	315671-32-0
Molecular Formula	C19H20N2O5
Molecular Weight	356.38 g/mol
Synonyms	2-Amino-7,7-dimethyl-4-(2-nitrophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylic acid methyl ester; Methyl 2-amino-4-(2-nitrophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate; 4H-Chromene-3-carboxylic acid, 2-amino-7,7-dimethyl-4-(2-nitrophenyl)-5-oxo-5,6,7,8-tetrahydro-, methyl ester; 315671-32-0; Chromene derivative intermediate; Tetrahydrochromene carboxylate.
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-7,7-Dimethyl-4-(2-Nitrophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.