Description

6-Amino-4-(2,3-Dimethoxyphenyl)-3-Phenyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the dihydropyranopyrazole class of heterocyclic compounds. Its complex molecular architecture makes it a critical building block for the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. This compound is essential for pharmaceutical companies and research institutions focused on developing new therapeutic agents, including potential kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates, especially those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new chemical entities.
• Biochemical Probe Development: Employed in the creation of specialized probes for studying biological mechanisms and target validation in cellular assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client-sponsored drug discovery programs.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	6-Amino-4-(2,3-Dimethoxyphenyl)-3-Phenyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	315246-21-0
Molecular Formula	C21H18N4O3
Molecular Weight	374.40 g/mol
Synonyms	6-Amino-3-phenyl-4-(2,3-dimethoxyphenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 1,4-Dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(2,3-dimethoxyphenyl)-3-phenyl-; 4-(2,3-Dimethoxyphenyl)-6-amino-3-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; Pyrano[2,3-c]pyrazole Carbonitrile Derivative; DHP Pyrazole Carbonitrile Intermediate
EINECS	Contact for details

Quality Control

Our 6-Amino-4-(2,3-Dimethoxyphenyl)-3-Phenyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.