Description

4H,5H-Pyrano[4,3-B]Pyran-3-Carbonitrile, 2-Amino-7-Methyl-4-(2-Nitrophenyl)-5-Oxo- is a high-value, heterocyclic organic compound characterized by a fused pyranopyran core structure functionalized with amino, cyano, and nitro-phenyl groups. This complex molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active compounds. The product is supplied to meet the stringent purity and consistency requirements of modern drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Agrochemical Development: Acts as a building block for creating new active ingredients with potential herbicidal or pesticidal properties.
• Organic Synthesis: Employed in academic and industrial research for developing new synthetic methodologies involving fused heterocyclic systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study enzyme function or cellular processes.

Basic Information

Product Name	4H,5H-Pyrano[4,3-B]Pyran-3-Carbonitrile, 2-Amino-7-Methyl-4-(2-Nitrophenyl)-5-Oxo-
CAS No.	315246-02-7
Molecular Formula	C₁₆H₁₁N₃O₄
Molecular Weight	309.28 g/mol
Synonyms	2-Amino-7-methyl-4-(2-nitrophenyl)-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile; 4H,5H-Pyrano[4,3-b]pyran-3-carbonitrile, 2-amino-7-methyl-4-(2-nitrophenyl)-5-oxo-; 2-Amino-4-(2-nitrophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile; 315246-02-7; Pyrano[4,3-b]pyran-3-carbonitrile derivative; Fused pyranopyran intermediate; Nitrophenyl pyranopyran carbonitrile
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. Each lot is analyzed using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support customer audits and can tailor specifications to meet specific project requirements under cGMP-like conditions where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.