Description

5-Acetyl-2-Amino-4-(4-Fluorophenyl)-6-Methyl-4H-Pyran-3-Carbonitrile is a high-purity, fluorinated pyran derivative serving as a critical advanced intermediate in modern organic synthesis. Its molecular architecture, featuring a 4-fluorophenyl substituent and multiple functional groups, makes it a valuable scaffold for constructing complex molecules with targeted biological and material properties. This compound is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry, agrochemical research, and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Medicinal Chemistry Scaffold: Used to synthesize libraries of novel heterocyclic compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated pyran core.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies in organic synthesis and fluorine chemistry.

Basic Information

Product Name	5-Acetyl-2-Amino-4-(4-Fluorophenyl)-6-Methyl-4H-Pyran-3-Carbonitrile
CAS No.	314767-33-4
Molecular Formula	C15H13FN2O2
Molecular Weight	272.28 g/mol
Synonyms	5-Acetyl-2-amino-4-(4-fluorophenyl)-6-methyl-4H-pyran-3-carbonitrile; 4H-Pyran-3-carbonitrile, 5-acetyl-2-amino-4-(4-fluorophenyl)-6-methyl-; 2-Amino-5-acetyl-4-(4-fluorophenyl)-6-methyl-4H-pyran-3-carbonitrile; 4-(4-Fluorophenyl)-5-acetyl-2-amino-6-methyl-4H-pyran-3-carbonitrile; 5-Acetyl-2-amino-4-(p-fluorophenyl)-6-methyl-4H-pyran-3-carbonitrile; CAS 314767-33-4
EINECS	Contact for details

Quality Control

Our 5-Acetyl-2-Amino-4-(4-Fluorophenyl)-6-Methyl-4H-Pyran-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.