Description

(1R)-6-Methoxy-1,2,3,4-Tetrahydronaphthalen-1-Amine is a chiral amine derivative of tetralin, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where stereochemical purity is paramount. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for producing high-value, optically active compounds, particularly in central nervous system (CNS) and cardiovascular drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in neurological and cardiovascular therapeutic areas.
• Asymmetric Catalysis Research: Used as a ligand precursor or a chiral auxiliary in the development of new catalytic systems.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients with specific biological activity.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals requiring defined stereochemistry.

Basic Information

Product Name	(1R)-6-Methoxy-1,2,3,4-Tetrahydronaphthalen-1-Amine
CAS No.	314019-10-8
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	(1R)-6-Methoxy-1,2,3,4-tetrahydro-1-naphthalenamine; (R)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine; (R)-1-Amino-6-methoxy-1,2,3,4-tetrahydronaphthalene; (R)-6-Methoxy-1-amino-1,2,3,4-tetrahydronaphthalene; (1R)-1-Amino-6-methoxy-1,2,3,4-tetrahydronaphthalene; (R)-6-Methoxy-1-tetralinamine; (R)-6-Methoxy-α-tetralinamine
EINECS	Contact for details

Quality Control

Our (1R)-6-Methoxy-1,2,3,4-Tetrahydronaphthalen-1-Amine is produced under strict quality management systems to ensure batch-to-batch consistency and high stereochemical purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to meet the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.