Description

3-(4-Amino-2-Methyl-Phenyl)-Chromen-2-One is a specialized organic compound belonging to the coumarin derivative family. This chemical serves as a crucial advanced intermediate in the synthesis of complex molecules, offering a versatile aromatic amine-coumarin scaffold. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and novel organic materials.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential drug candidates, particularly those targeting neurological or inflammatory pathways.
• Fluorescent Probe Synthesis: Used to create coumarin-based fluorescent dyes and sensors for biochemical and diagnostic applications due to its inherent fluorophore structure.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for developing emissive or charge-transporting materials in electronic displays and lighting.
• Agrochemical Research: Intermediate in the development of novel herbicides or fungicides that leverage the biological activity of coumarin derivatives.
• Fine Chemical Synthesis: Employed in custom and contract synthesis for creating complex, high-value specialty chemicals.
• Academic & Industrial R&D: Used in chemical research to study structure-activity relationships and develop new synthetic methodologies.

Basic Information

Product Name	3-(4-Amino-2-Methyl-Phenyl)-Chromen-2-One
CAS No.	313701-57-4
Molecular Formula	C16H13NO2
Molecular Weight	251.28 g/mol
Synonyms	3-(4-Amino-2-methylphenyl)-2H-chromen-2-one; 3-(4-Amino-2-methylphenyl)coumarin; 4-Amino-2-methylphenylcoumarin; 2H-1-Benzopyran-2-one, 3-(4-amino-2-methylphenyl)-; 3-(4-Amino-o-tolyl)coumarin; 7-Amino-5-methylcoumarin (common misnomer, verify structure); 3-(4-Amino-2-methylphenyl)-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our 3-(4-Amino-2-Methyl-Phenyl)-Chromen-2-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.