Description

·L-Alanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-3-(Phenylseleno)- CAS NO 312746-41-1 is a specialized, protected amino acid derivative featuring a phenylseleno moiety. This compound is a critical building block in solid-phase peptide synthesis (SPPS), where it enables the controlled introduction of selenium-containing amino acids for research into selenoproteins and novel peptide architectures. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in advanced peptide chemistry, medicinal chemistry, and the study of redox-active biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the incorporation of 3-selenoalanine into custom peptide sequences.
• Selenoprotein Research: Used in the synthesis of peptides that mimic or model the active sites of selenoenzymes like glutathione peroxidase.
• Medicinal Chemistry & Drug Discovery: Serves as a precursor for creating peptide-based drug candidates with enhanced stability or novel redox properties.
• Chemical Biology Probes: Enables the synthesis of labeled or modified peptides for studying protein structure, function, and interactions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and peptide science.

Basic Information

Product Name	·L-Alanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-3-(Phenylseleno)-
CAS No.	312746-41-1
Molecular Formula	C24H21NO4Se
Molecular Weight	466.39 g/mol
Synonyms	Fmoc-3-seleno-L-alanine(Phenyl); Fmoc-L-3-phenylselenoalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(phenylseleno)-L-alanine; Fmoc-SelAla(Ph)-OH; Fmoc-Ala(SePh)-OH; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-3-(phenylselanyl)propanoic acid; 3-Phenylseleno-L-alanine, N-Fmoc derivative
EINECS	Contact for details

Quality Control

Our ·L-Alanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-3-(Phenylseleno)- is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. Keep the material in a cool, dry, and well-ventilated area away from incompatible substances.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.