Description

Benzenepropanol, 4-(Trifluoromethyl)-, 1-(4-Methylbenzenesulfonate) is a specialized organic intermediate featuring a benzenepropanol core functionalized with a trifluoromethyl group and a tosylate ester. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly where the introduction of a fluorinated aromatic moiety is required. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring metabolic stability enhancement via fluorine incorporation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer chains, altering properties like chemical resistance, thermal stability, and surface characteristics.
• Cross-Coupling Reactions: The tosylate group acts as a good leaving group, making this compound a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl systems.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating compound libraries for high-throughput screening.

Basic Information

Item	Detail
Product Name	Benzenepropanol, 4-(Trifluoromethyl)-, 1-(4-Methylbenzenesulfonate)
CAS No.	312690-19-0
Molecular Formula	C17H17F3O3S
Molecular Weight	358.38 g/mol
Synonyms	4-(Trifluoromethyl)benzenepropanol 1-(4-Methylbenzenesulfonate); 3-[4-(Trifluoromethyl)phenyl]propyl 4-methylbenzenesulfonate; 3-(4-Trifluoromethylphenyl)propyl tosylate; p-Trifluoromethylphenpropyl tosylate; Tosylate ester of 3-(4-trifluoromethylphenyl)-1-propanol; α,α,α-Trifluoro-p-tolylpropyl tosylate
EINECS	Contact for details

Quality Control

Every batch of our Benzenepropanol, 4-(Trifluoromethyl)-, 1-(4-Methylbenzenesulfonate) undergoes rigorous analytical testing to ensure identity, purity, and consistency. We employ advanced techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.