Description

6-Amino-3-(tert-Butyl)-4-(2-Chloro-6-Fluorophenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyranopyrazole chemical class. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, especially in oncology and central nervous system (CNS) drug research.
• Chemical Biology Research: Used as a scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Process Chemistry Development: Serves as a standard or reference material for scaling up synthetic routes and optimizing yield and purity in API manufacturing.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development of patent-protected drug candidates.
• Academic Research: Utilized in university and institutional labs for investigating new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	6-Amino-3-(tert-Butyl)-4-(2-Chloro-6-Fluorophenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	312265-20-6
Molecular Formula	C₁₇H₁₆ClFN₄O
Molecular Weight	346.79 g/mol
Synonyms	6-Amino-3-tert-butyl-4-(2-chloro-6-fluorophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 1,4-Dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-3-(1,1-dimethylethyl)-4-(2-chloro-6-fluorophenyl)-; 312265-20-6; tert-Butyl pyranopyrazole carbonitrile derivative; 4-(2-Chloro-6-fluorophenyl)pyranopyrazole intermediate
EINECS	Contact for details

Quality Control

Our production of 6-Amino-3-(tert-Butyl)-4-(2-Chloro-6-Fluorophenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with research and development grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.