Description

6-Amino-3-tert-Butyl-4-(2,6-Dichlorophenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), offering a precise scaffold for medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on creating new therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as an intermediate in the research and production of novel pesticides and herbicides.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & Institutional Research: Utilized in universities and research institutes for studying heterocyclic chemistry and reaction mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects.

Basic Information

Product Name	6-Amino-3-tert-Butyl-4-(2,6-Dichlorophenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	312265-19-3
Molecular Formula	C₁₇H₁₆Cl₂N₄O
Molecular Weight	363.24 g/mol
Synonyms	6-Amino-3-(tert-butyl)-4-(2,6-dichlorophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 1,4-Dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-3-(1,1-dimethylethyl)-4-(2,6-dichlorophenyl)-; 3-tert-Butyl-6-amino-4-(2,6-dichlorophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 312265-19-3; AKOS BB-1020; 4-(2,6-Dichlorophenyl)-6-amino-3-tert-butyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Amino-3-tert-Butyl-4-(2,6-Dichlorophenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.