Description

2-Ethoxybenzylzinc Chloride is an organozinc reagent, a versatile building block in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, specifically through palladium-catalyzed cross-coupling reactions, which are fundamental to constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity, reliable intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of novel active pharmaceutical ingredients (APIs) via Negishi and other cross-coupling reactions.
• Agrochemical Synthesis: Used to construct complex heterocyclic and aromatic structures found in modern herbicides, fungicides, and insecticides.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers, by introducing specific aromatic ether functionalities.
• Fine Chemical Production: Facilitates the scalable, selective introduction of the 2-ethoxybenzyl moiety into target molecules for specialty chemicals.
• Academic & R&D Laboratories: A critical tool for methodological development in synthetic organic chemistry and exploring new reaction pathways.

Basic Information

Product Name	2-Ethoxybenzylzinc Chloride
CAS No.	308796-28-3
Molecular Formula	C9H11ClOZn
Molecular Weight	235.99 g/mol
Synonyms	(2-Ethoxybenzyl)zinc chloride; Zinc, chloro(2-ethoxybenzyl)-; 2-Ethoxybenzylzinc chloride solution; (2-Ethoxyphenyl)methylzinc chloride; Chloro(2-ethoxybenzyl)zinc; 2-Ethoxybenzyl zinc chloride; o-Ethoxybenzylzinc chloride
EINECS	Contact for details

Quality Control

Our 2-Ethoxybenzylzinc Chloride is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including titration for active zinc content and spectroscopic methods (NMR, IR) for structural confirmation and purity assessment. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This material is hygroscopic (moisture-sensitive) and must be handled in a dry, controlled environment using standard Schlenk or glovebox techniques to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in Tetrahydrofuran (Typical)
Assay (Titration)	≥ 95%
Identification (NMR/IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.