Description

2-(Methylthio)Phenylzinc Iodide is a highly reactive organozinc reagent, specifically an arylzinc halide, used in modern organic synthesis. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity building blocks for creating novel compounds.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing the 2-(methylthio)phenyl moiety into target molecules via Negishi and related cross-coupling reactions.
• Agrochemical Research & Development: Used in the synthesis of novel active ingredients, such as herbicides and fungicides, that require specific aryl sulfide functionalities.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Applications: Employed in the development of organic electronic materials, including OLEDs and semiconductors, where controlled aryl group incorporation is critical.
• Fine Chemical Manufacturing: Facilitates the production of complex, high-value specialty chemicals and fragrances through selective coupling steps.
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	2-(Methylthio)Phenylzinc Iodide
CAS No.	308796-24-9
Molecular Formula	C7H7ISZn
Molecular Weight	315.46 g/mol
Synonyms	(2-Methylsulfanylphenyl)zinc iodide; Zinc, [2-(methylthio)phenyl]iodo-; 2-(Methylmercapto)phenylzinc iodide; (2-Methylthiophenyl)zinc iodide; 2-(Methylthio)benzenylzinc iodide; 2-Methylthiobenzenezinc iodide; (o-Methylthiophenyl)zinc iodide
EINECS	Contact for details

Quality Control

Our 2-(Methylthio)Phenylzinc Iodide is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes rigorous analytical testing, including titration for active zinc content and spectroscopic identification. We provide comprehensive Certificates of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or other ethereal solvents), and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). For optimal stability, store the sealed reagent bottle under an inert gas (argon or nitrogen) atmosphere at 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress and maintain solution integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure
Water Content (Karl Fischer)	< 500 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.