Description

1-Methylbutylzinc Bromide is a highly reactive organozinc reagent, specifically a secondary alkylzinc halide. This compound is a valuable synthetic building block in organic chemistry, enabling efficient carbon-carbon bond formation through cross-coupling and nucleophilic addition reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the Negishi cross-coupling reaction to introduce the 1-methylbutyl moiety into active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Manufacturing: Used in the production of specialized pesticides and herbicides where the specific branched alkyl chain is required for biological activity.
• Advanced Material Precursor: Serves as an organometallic precursor in materials science for the development of novel polymers or functionalized surfaces.
• Fine Chemical Production: Employed in the synthesis of flavors, fragrances, and other high-value specialty chemicals requiring selective alkylation.
• Catalyst and Ligand Development: Used in research for the preparation of novel zinc-based catalysts or as a reactant to generate other organometallic complexes.
• Academic and Industrial R&D: A critical tool for methodological development in synthetic organic chemistry laboratories exploring new catalytic cycles and reaction pathways.

Basic Information

Product Name	1-Methylbutylzinc Bromide
CAS No.	308796-07-8
Molecular Formula	C5H11BrZn
Molecular Weight	216.44 g/mol
Synonyms	sec-Pentylzinc Bromide; (1-Methylbutyl)zinc Bromide; Zinc, bromo(1-methylbutyl)-; Bromo(1-methylbutyl)zinc; Bromo(sec-pentyl)zinc; 1-Methylbutylzinc Bromide solution; sec-Amylzinc Bromide; (sec-Pentyl)zinc Bromide
EINECS	Contact for details

Quality Control

Our 1-Methylbutylzinc Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is analyzed to confirm identity, purity, and concentration (typically supplied as a solution in a specified organic solvent). A comprehensive Certificate of Analysis (COA) detailing assay results, solvent content, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions to maintain stability. This compound is moisture-sensitive (hygroscopic) and easily oxidized; all handling and aliquoting must be performed using standard Schlenk line or glovebox techniques under a dry, oxygen-free environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (Zn basis)	≥ 95%
Solvent Content (GC)	Balance

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.