Description

2 3 4 5 6-Pentafluorobenzylzinc Chloride is a highly reactive organozinc reagent, a crucial building block for introducing the pentafluorobenzyl group into complex molecular frameworks. Its value lies in enabling efficient carbon-carbon bond formation under mild conditions, which is essential for synthesizing advanced fluorinated compounds. This material is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the unique properties of fluorine to modulate bioavailability and metabolic stability.
• Agrochemical Development: Used in the synthesis of novel fluorinated pesticides, herbicides, and fungicides, where the pentafluorobenzyl moiety can enhance activity and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for specialized ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Advanced Material Research: Employed in the development of fluorinated liquid crystals, polymers, and electronic materials that require specific dielectric or surface properties.
• Radiochemistry and Tracer Synthesis: Potential use in the preparation of fluorinated precursors for positron emission tomography (PET) tracer development.
• Custom Fluorination Chemistry: A versatile tool for contract research organizations (CROs) and fine chemical manufacturers performing bespoke fluorination for client projects.

Basic Information

Product Name	2 3 4 5 6-Pentafluorobenzylzinc Chloride
CAS No.	308796-02-3
Molecular Formula	C7H2ClF5Zn
Molecular Weight	287.93 g/mol
Synonyms	(Pentafluorobenzyl)zinc Chloride; Zinc, chloropentafluorobenzyl-; Pentafluorobenzylzinc Chloride Solution; 2,3,4,5,6-Pentafluorobenzylzinc Chloride; (Perfluorobenzyl)zinc Chloride; C6F5CH2ZnCl; Pentafluorobenzyl Zinc Chloride Reagent
EINECS	Contact for details

Quality Control

Every batch of 2 3 4 5 6-Pentafluorobenzylzinc Chloride is manufactured and handled under strict inert atmosphere conditions to ensure integrity. Our quality assurance includes rigorous analysis to confirm identity, purity, and solution concentration. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as assay, solvent content, and absence of major impurities. We adhere to cGMP principles where applicable to support our customers' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. The compound is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be kept sealed and only opened in a dry, inert environment. For long-term stability, storage at lower temperatures (e.g., -20°C) under inert gas is recommended.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (GC/HPLC)	≥ 95% (by GC area)
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.