Description

4-Methyl-2-Pyridylzinc Bromide is a highly reactive organozinc reagent, specifically a pyridylzinc halide, widely used in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and reliable building blocks for drug discovery and fine chemical synthesis. CAS NO 308795-93-9.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing the 4-methyl-2-pyridyl moiety into target molecules during the research and development of new active pharmaceutical ingredients (APIs).
• Negishi Cross-Coupling Reactions: Used in palladium-catalyzed couplings with organic halides (e.g., aryl, vinyl, alkynyl halides) to form biaryl and other complex structures.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized pyridine-containing ligands used in homogeneous catalysis.
• Agrochemical Research: Employed in the synthesis of novel compounds with potential herbicidal, insecticidal, or fungicidal activity.
• Material Science: Useful in the development of organic electronic materials, such as those for OLEDs, by constructing specific conjugated systems.
• Academic & Process R&D: A valuable tool for methodological development in organic synthesis and for scaling up synthetic routes in process chemistry.

Basic Information

Product Name	4-Methyl-2-Pyridylzinc Bromide
CAS No.	308795-93-9
Molecular Formula	C6H7BrNZn
Molecular Weight	238.42 g/mol
Synonyms	2-(4-Methylpyridyl)zinc bromide; (4-Methyl-2-pyridinyl)zinc bromide; Zinc, bromo(4-methyl-2-pyridinyl)-; 4-Methyl-2-pyridylzinc bromide solution; 2-Pyridylzinc bromide, 4-methyl-; Bromo(4-methyl-2-pyridinyl)zinc
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Pyridylzinc Bromide is manufactured under strict quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot is analyzed to confirm identity, purity, and concentration (typically supplied as a solution in THF or other ethereal solvents). A comprehensive Certificate of Analysis (COA) detailing assay (by titration), residual moisture, and other relevant parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures (typically between 2°C and 8°C for solutions). Handle and store only in a dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (HPLC)	≥ 95% (Pyridine basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.