Description

2-Amino-4-(1H-Indol-3-Yl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is a high-value, multifunctional heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular architecture, combining chromene and indole moieties, makes it a versatile building block for the development of novel pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and the synthesis of complex organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system disorders, inflammation, and microbial infections.
• Medicinal Chemistry Research: Serves as a privileged scaffold for constructing compound libraries in high-throughput screening for new biological activities.
• Agrochemical Development: Used in research for creating novel pesticides and herbicides due to its complex heterocyclic structure.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct more complex polycyclic frameworks and natural product analogs.
• Material Science Research: Investigated as a precursor for organic electronic materials and fluorescent dyes owing to its conjugated system.
• Academic & Contract Research: Essential reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic chemistry.

Basic Information

Product Name	2-Amino-4-(1H-Indol-3-Yl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile
CAS No.	307552-88-1
Molecular Formula	C20H19N3O2
Molecular Weight	333.39 g/mol
Synonyms	3-Cyano-2-amino-4-(3-indolyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene; 2-Amino-4-(1H-indol-3-yl)-7,7-dimethyl-5-oxo-4H,5H,6H,7H,8H-chromene-3-carbonitrile; 4H-Chromene-3-carbonitrile, 2-amino-4-(1H-indol-3-yl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-; Tetrahydrochromene-carbonitrile derivative; Indole-chromene hybrid molecule; Knoevenagel-Indole adduct
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(1H-Indol-3-Yl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.