Description

7-[(2-Chloro-6-Fluorophenyl)Methoxy]-6-Methyl-2,3-Dihydro-1H-Cyclopenta[C]Chromen-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and anti-inflammatory drug discovery pipelines.

Application

• Critical pharmaceutical intermediate for the synthesis of proprietary drug candidates.
• Key building block in medicinal chemistry research and structure-activity relationship (SAR) studies.
• Precursor for the development of potential kinase inhibitors and other targeted therapies.
• Used in preclinical and process chemistry for scale-up and optimization.
• Reference standard for analytical method development and quality control in API manufacturing.
• Starting material for synthesizing complex heterocyclic compounds in advanced organic chemistry.

Basic Information

Product Name	7-[(2-Chloro-6-Fluorophenyl)Methoxy]-6-Methyl-2,3-Dihydro-1H-Cyclopenta[C]Chromen-4-One
CAS No.	307549-08-2
Molecular Formula	C20H16ClFO3
Molecular Weight	358.79 g/mol
Synonyms	7-[(2-Chloro-6-fluorophenyl)methoxy]-6-methyl-2,3-dihydro-1H-cyclopenta[c]chromen-4-one; 6-Methyl-7-[(2-chloro-6-fluorobenzyl)oxy]-2,3-dihydro-1H-cyclopenta[c]chromen-4-one; 307549-08-2; Cyclopenta[c]chromen-4-one derivative; Fluorobenzyloxy chromenone; Chlorofluorobenzyl chromenone intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch is subjected to comprehensive analytical characterization using techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide regulatory starting material documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.