Description

(1,3-Dioxolan-2-Ylethyl)Zinc Bromide is a highly reactive organozinc reagent, specifically a functionalized zincate complex. This compound is valued for its role as a versatile nucleophile in advanced organic synthesis, enabling the formation of carbon-carbon bonds under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules and novel intermediates.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the introduction of functionalized ethyl units in the synthesis of active pharmaceutical ingredients (APIs).
• Cross-Coupling Reactions: Used as an organometallic nucleophile in Negishi and related cross-coupling reactions to construct complex molecular architectures.
• Fine Chemical Manufacturing: Enables the production of specialty chemicals, flavors, and fragrances requiring precise carbon chain elongation.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and insecticides through targeted alkylation steps.
• Material Science Precursor: Serves as a starting material for the development of zinc-containing organic frameworks and polymers.
• Academic & Process R&D: A critical tool in methodological development and scalable route design for complex organic molecules.

Basic Information

Product Name	(1,3-Dioxolan-2-Ylethyl)Zinc Bromide
CAS No.	307531-83-5
Molecular Formula	C5H9BrO2Zn
Molecular Weight	246.42 g/mol
Synonyms	2-(1,3-Dioxolan-2-yl)ethylzinc bromide; (2-(1,3-Dioxolan-2-yl)ethyl)zinc bromide; Zinc, bromo[2-(1,3-dioxolan-2-yl)ethyl]-; (1,3-Dioxolan-2-ylethyl)zinc bromide solution; 2-(1,3-Dioxolan-2-yl)ethan-1-ylzinc bromide
EINECS	Contact for details

Quality Control

Our (1,3-Dioxolan-2-Ylethyl)Zinc Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and concentration (typically supplied as a solution in THF or other suitable solvents). Certificates of Analysis (COA) detailing assay, solvent content, and impurity profiles are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label. Due to its properties as a strong base/organic solvent, easily oxidized, and highly volatile compound, it must be handled in a dry, well-ventilated environment using appropriate safety measures. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR/IR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (Zn basis)	≥ 95%
Solvent Content (GC)	Balance

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.