Description

(1,3-Dioxan-2-Ylethyl)Zinc Bromide is a highly reactive organozinc reagent, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation, particularly in the synthesis of complex molecules where traditional methods are inefficient. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable intermediates for cross-coupling and nucleophilic addition reactions.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing complex molecular scaffolds in active pharmaceutical ingredient (API) development.
• Negishi Cross-Coupling Reactions: Used to form carbon-carbon bonds with high selectivity and functional group tolerance, critical for fine chemical manufacturing.
• Nucleophilic Addition to Carbonyls: Enables the synthesis of secondary and tertiary alcohols from aldehydes and ketones.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Advanced Material Precursors: Used in the development of organic electronic materials and specialty polymers.
• Asymmetric Synthesis: Serves as a precursor for chiral organozinc reagents in enantioselective transformations.

Basic Information

Product Name	(1,3-Dioxan-2-Ylethyl)Zinc Bromide
CAS No.	307531-82-4
Molecular Formula	C6H11BrO2Zn
Molecular Weight	260.45 g/mol
Synonyms	2-(1,3-Dioxan-2-yl)ethylzinc bromide; (2-(1,3-Dioxan-2-yl)ethyl)zinc bromide; Zinc, bromo[2-(1,3-dioxan-2-yl)ethyl]-; (1,3-Dioxan-2-ylethyl)zinc bromide solution; Organozinc bromide reagent 307531-82-4
EINECS	Contact for details

Quality Control

Every batch of (1,3-Dioxan-2-Ylethyl)Zinc Bromide is produced and handled under strict inert atmosphere conditions to ensure integrity. Our products undergo rigorous quality testing, including titration for active zinc content and spectroscopic analysis, to ensure compliance with high-purity standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or other solvents), and impurity profile is available upon request.

Storage

Preserve in a tightly closed container, protected from light. This compound is highly volatile, hygroscopic (moisture-sensitive), and easily oxidized. It must be stored under a dry, inert atmosphere (argon or nitrogen) at recommended temperatures of 2-8°C for long-term stability. The container should be kept in a cool, dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (Zinc content)	≥ 95%
Solvent	Tetrahydrofuran (THF) or other specified solvent

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.