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5-Ethoxycarbonyl-2-Furylzinc Bromide CAS NO 307531-81-3


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CAS No.:307531-81-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Ethoxycarbonyl-2-Furylzinc Bromide is a highly reactive organozinc reagent, specifically a functionalized furylzinc bromide derivative. This compound is a critical building block in modern synthetic organic chemistry, enabling the efficient and selective introduction of the 5-ethoxycarbonyl-2-furyl moiety into complex molecular frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel heterocyclic compounds and active ingredients.

Application

  • Pharmaceutical Intermediates: Key reagent for the synthesis of novel drug candidates, particularly those containing functionalized furan rings.
  • Agrochemical Synthesis: Used in the development of new pesticides and herbicides where the furyl group imparts specific biological activity.
  • Cross-Coupling Reactions: Essential component in Negishi, Kumada, and other transition-metal catalyzed cross-coupling reactions to form carbon-carbon bonds.
  • Material Science Precursors: Building block for creating organic electronic materials, ligands for catalysts, and specialty polymers.
  • Academic & Industrial R&D: A valuable tool for methodology development and exploring new synthetic pathways in organic chemistry laboratories.
  • Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances intermediates.

Basic Information

Product Name 5-Ethoxycarbonyl-2-Furylzinc Bromide
CAS No. 307531-81-3
Molecular Formula C7H7BrO3Zn
Molecular Weight 276.43 g/mol
Synonyms Ethyl 5-(bromozincio)furan-2-carboxylate; 2-Furancarboxylic acid, 5-(bromozincio)-, ethyl ester; 5-(Ethoxycarbonyl)-2-furylzinc bromide; Bromo(5-ethoxycarbonyl-2-furyl)zinc; Zinc, bromo(5-ethoxycarbonyl-2-furyl)-; (5-Ethoxycarbonylfuran-2-yl)zinc bromide
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Quality Control

Every batch of 5-Ethoxycarbonyl-2-Furylzinc Bromide is manufactured and handled under strict inert atmosphere conditions to ensure stability and reactivity. Our products undergo rigorous quality testing, including titration for active zinc content and spectroscopic analysis, to ensure compliance with stringent R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or other solvents), and stability indicators is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures between 2°C and 8°C for solutions. For the solid form, store in a freezer at -20°C or below under inert gas. Keep away from strong acids and oxidizing agents. Use appropriate ventilation and handling procedures for air-sensitive materials.

Specification

Item Specification
Appearance (Solution) Colorless to pale yellow solution
Concentration 0.5 M in THF (Typical, other solvents available)
Assay (Titration) ≥ 95% (as C7H7BrO3Zn)
Identity (NMR/IR) Conforms to structure
Water Content (KF) < 500 ppm
Stability Stable under inert atmosphere at specified temperature

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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