Description

3-Fluorophenylzinc Iodide is a versatile organozinc reagent, a key building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, specifically through cross-coupling reactions like Negishi coupling, which is critical for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for introducing the 3-fluorophenyl moiety into target molecules during the research and development of new drug candidates.
• Negishi Cross-Coupling Reactions: Used as a transmetalating agent with palladium or nickel catalysts to form biaryl and other C-C bonds with high selectivity and functional group tolerance.
• Agrochemical Manufacturing: Employed in the synthesis of herbicides, fungicides, and insecticides that incorporate fluorinated aromatic systems for enhanced efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and polymerization processes.
• Material Science Research: Used in the synthesis of fluorinated organic semiconductors, liquid crystals, and polymers for electronic and optical applications.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global chemical industry.

Basic Information

Item	Details
Product Name	3-Fluorophenylzinc Iodide
CAS No.	307496-28-2
Molecular Formula	C6H4FZnI
Molecular Weight	287.39 g/mol
Synonyms	(3-Fluorophenyl)zinc iodide; Zinc, (3-fluorophenyl)-, iodide (1:1); 3-Fluorophenylzinc iodide solution; m-Fluorophenylzinc iodide; 1-Fluoro-3-(iodozincio)benzene; Organozinc reagent 3-FC6H4ZnI
EINECS	Contact for details

Quality Control

Our 3-Fluorophenylzinc Iodide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. We provide comprehensive Certificates of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or other ethers), and impurity profiles. Our quality systems are designed to meet the exacting standards required for GMP intermediates and research-grade chemicals, ensuring reliability for your most critical synthetic steps.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and reacts with strong bases. It must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For solutions, typical recommended storage temperature is 2-8°C. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution (typically in THF)
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure
Water Content (KF)	< 500 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.